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How an adjuvant can modulate the immune response against coccidiosis in poultry

11 June 2020, at 9:00am

EVALON® is a live coccidiosis vaccine against avian coccidiosis in poultry composed of E. acervulina, E. brunetti, E. maxima, E. necatrix and E. tenella. All the strains have been selected to maximize immunogenicity. Avian Eimeria have a complex life cycle with a combination of exogenous and endogenous stages that trigger the immune system of the host. However, Eimeria parasites have also been described as being highly elusive to the immune system as well as producing chemokines than can slow or inhibit the immune response (Jang 2011, Schmid 2014, Miska 2013).

Levels of IL-2 detected in vaccinated birds:
Levels of IL-2 detected in vaccinated birds:

Higher levels of IL-2 were detected in those birds which received EVALON® together with HIPRAMUNE®T compared to the group that received the vaccine alone.

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